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The crystal structure of LiCoO
2020-02-10

The crystal structure of LiCoO2 is presented in Fig. 1. We can notice that the Li and Co atoms occupy the centers of two different edge-sharing [CoO6]-octahedra, which results in formation of separate Li and Co layers. Hence, the layered structure of LiMO2 is able to intercalate lithium into transit
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The final test that was performed was to determine whether
2020-02-10

The final test that was performed was to determine whether the trigger points of the current limiters are stable across a wide temperature range. This test was performed within a thermal-vacuum chamber on each current limiter individually. All the current limiter trip currents were set to approximat
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br Introduction Concrete is one of the
2020-02-10

Introduction Concrete is one of the most commonly used materials in the construction industry and its raw material is available throughout the world. Concrete is derived from ordinary Portland cement and is used for the construction and development of infrastructures. Research shows that demand f
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Our study found a significant association between the degree
2020-02-10

Our study found a significant association between the degree of primary tumor lobulation and EGFR mutations status (P EGFR R 59-022 status. However, only a small portion of these previous studies included the evaluation of lobulation, and almost all of them reported no association between EGFR mutat
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CXCR is not only critical in the B cell lineage
2020-02-10

CXCR5 is not only critical in the B cell lineage in FL. A high proportion of CXCR5-expressing follicular helper T cells (TFH) were observed in FL but not in closely related DLBCL [141] and further investigation revealed that FL regulatory T cells (Tregs) used a CXCL13-CXCR5 autocrine loop for positi
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The two most important biological machineries
2020-02-10

The two most important biological machineries controlling proteostasis, PQC, and degradation are autophagy and the ubiquitin-proteasome system (UPS) (). Autophagy is a lysosome-dependent, tightly regulated catabolic process that degrades unwanted cell organelles and cytoplasmic constituents in lysos
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br Methods br Results br
2020-02-10

Methods Results Discussion To our knowledge, this is the first report to investigate the association between DBH genotype and pDβH activity in Han Chinese subjects. We also examined the relationship among DBH gene polymorphisms, pDβH activity and cognitive function in patients with schizoph
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The activity of chromenones bearing heteroaryl
2020-02-10

The activity of chromenones bearing heteroaryl groups at the 8-position is summarised in . Replacement of the 8-phenyl substituent of by a thiophen-2-yl group ( and ) did not improve DNA-PK inhibitory activity, although the 4-phenylthiophen-2-yl derivative (), together with the bithiophene analogue
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The molecular docking data supported the potential interacti
2020-02-10

The molecular docking data supported the potential interaction of lapachol and the synthetic naphthoquinonolyl compounds with the PfDHODH enzyme as the putative mechanism of action and the inhibition of parasite growth in vitro. In general, compounds fit well into the binding pocket of PfDHODH, the
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Kluveromyces lactisSimilar to S cerevisiae K lactis
2020-02-10

Kluveromyces lactisSimilar to S. cerevisiae, K. lactis is a facultative anaerobic respiratory yeast, which lacks Complex I in its mitochondrial respiratory chain. However, both yeasts differ regarding their respiratory-fermentative metabolism as K. lactis exhibits a greater use of the pentose phosph
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br Use of recombinant collagen to study DDR
2020-02-10

Use of recombinant collagen to study DDR–collagen interactions Synthetic peptides have proven highly valuable in replicating the characteristics of collagen and in defining the sites on collagen essential for binding and studying protein–collagen interactions. There are, however, disadvantages to
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The repeat sequence TTAGGG of telomere
2020-02-08

The repeat sequence “TTAGGG” of telomere could be directly recognized by TERF1. TERF1 is indispensable for the maintenance of telomere Azacyclonol structure and integrity (Tan et al., 2017). Trf1 genetic depletion in vivo induces a persistent DNA damage response and telomere uncapping, which effect
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In contrast to inflammatory cytokines
2020-02-08

In contrast to inflammatory cytokines, TGF-β has immunosuppressive properties yet is also important for tissue imprinting immune cell function during development [23]. Salivary gland (SG) ILCs, in addition to liver and intestinal intraepithelial ILC1, express markers denoting tissue residency and TG
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The possibility of harm with DPP inhibitors
2020-02-08

The possibility of harm with DPP-4 inhibitors in patients with clinically overt heart failure has been recently highlighted by the results of the VIVIDD (Vildagliptin in Ventricular Dysfunction Diabetes) trial (68), the only trial to date that has been designed to evaluate the effects of a DPP-4 inh
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Similarly to other investigations the present study found
2020-02-08

Similarly to other investigations, the present study found that ZEA in high concentrations decreases viability of both normal (Liu et al., 2018, Zheng et al., 2018a, Zheng et al., 2018b) and cancer INCB 018424 mg (Khosrokhavar et al., 2009, Kowalska et al., 2017). The toxic effect of ZEA observed by
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